Piperidine, 4-(3,5-dichlorophenyl)-

Piperidine, 4-(3,5-dichlorophenyl)- - Names and Identifiers

Name	4-(3,5-dichlorophenyl)piperidine
Synonyms	4-(3,5-dichlorophenyl)piperidine 4-(3,5-Dichloro-phenyl)-piperidi Piperidine, 4-(3,5-dichlorophenyl)- 4-(3,5-Dichlorophenyl)piperidine HCl 4-(3,5-DICHLOROPHENYL)PIPERIDINE HYDROCHLORIDE
CAS	475653-05-5
InChI	InChI=1/C11H13Cl2N/c12-10-5-9(6-11(13)7-10)8-1-3-14-4-2-8/h5-8,14H,1-4H2

Piperidine, 4-(3,5-dichlorophenyl)- - Physico-chemical Properties

Molecular Formula	C11H13Cl2N
Molar Mass	230.13
Density	1.207
Boling Point	317.0±42.0 °C(Predicted)
Flash Point	145.5°C
Vapor Presure	0.000395mmHg at 25°C
pKa	10.03±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.549

Piperidine, 4-(3,5-dichlorophenyl)- - Introduction

4-(3,5-dichlorophenyl)piperidine is an organic compound with the chemical formula C12H14Cl2N2. It has the form of a white crystalline solid with a piperidine ring and a 3,5-dichlorophenyl substituent in the molecule.

This compound is often used as an intermediate or material in organic synthesis, and has certain applications in pharmaceutical research and manufacturing. It can be used as a potential drug molecular skeleton for the synthesis of biologically active compounds. In addition, it can also be used in organic synthesis reactions, such as C- H bond activation of aromatic hydrocarbons, nucleophilic substitution and other reactions.

The method for preparing 4-(3,5-dichlorophenyl)piperidine is usually obtained by ketonizing reaction of piperidine with 3,5-dichlorobenzaldehyde. The reaction can be carried out in the presence of a suitable solvent and a catalyst.

Regarding safety information, 4-(3,5-dichlorophenyl)piperidine may have certain toxicity, so appropriate safety measures should be taken when using or handling. If it is necessary to use this compound, it is recommended to do so under suitable ventilation and wearing personal protective equipment, such as gloves and goggles.

In addition, the compound should be stored in a dry, cool place, away from fire and oxidizing agents. Avoid direct contact with skin and eyes during handling, and avoid ingesting or inhaling its dust. If accidental contact occurs, rinse immediately with plenty of water and seek medical help. For safety reasons, you should understand the detailed safety operation instructions before use.

Last Update：2024-04-09 20:52:54